Martin Luther University Halle-Wittenberg

Contact

Prof. Dr. Sonja Keßler

room 417.1
Kurt-Mothes-Str. 3
06120 Halle/Saale

ORCID: 0000-0002-8591-851

Sekretariat: Frau A. Ernst

phone: +49 345 55 25003
fax: +49 345 55 27021

room 417.2
Kurt-Mothes-Str. 3
06120 Halle/Saale

How to reach us    

Further settings

Login for editors

Pharmacology and Toxicology for Natural Sciences

Research Group Experimental Pharmacology for Natural Sciences

Kessler lab: April 2023. f.l.t.r. Kathrin Dietze, Lisa Ahne, Susanne Franke, Angela Ernst, Johannes Kipp, beatrice Starke, Frank Erdmann, Manuela Thiemicke, Kevin Ziegenhagel, Sonja Kessler, Linus Wolf, Sandra Kendzia

Kessler lab: April 2023. f.l.t.r. Kathrin Dietze, Lisa Ahne, Susanne Franke, Angela Ernst, Johannes Kipp, beatrice Starke, Frank Erdmann, Manuela Thiemicke, Kevin Ziegenhagel, Sonja Kessler, Linus Wolf, Sandra Kendzia

Kessler lab: April 2023. f.l.t.r. Kathrin Dietze, Lisa Ahne, Susanne Franke, Angela Ernst, Johannes Kipp, beatrice Starke, Frank Erdmann, Manuela Thiemicke, Kevin Ziegenhagel, Sonja Kessler, Linus Wolf, Sandra Kendzia

Welcome to the website of the research group Experimental Pharmacology for Natural Sciences at the Institute of Pharmacy.

Further information on projects, staff, and teaching can be found by using the links of the menu.

News

New mechanism in cardiac remodeling and cardiomyopathy! The first paper from a great collaboration with our Israeli colleagues has been published. 10.1038/s42003-023-05547-x    

Also take a look at the press reports:

"Discovery paves the way for innovative therapeutic strategies in managing cardiac conditions"   

"RNA binding protein IGF2BP2 identified as key player in stress-induced dilated cardiomyopathy"   

"Unveiling heart's hidden hero: RNA binding protein IGF2BP2 identified as key player in stress-induced dilated cardiomyopathy"   

"When a big heart isn't a good thing"   

Interested in epigenetics of steatosis? Read our recent article about epigenetic changes in fatty liver disease! https://rdcu.be/dgfMN   

Our paper on the role of IGF2BP2 in colon cancer chemoresistance has been accepted for publication in Molecular Cancer! Check the full paper here:

https://rdcu.be/ddnIb   

Lab event

Pharmafasching

Nice evening at the "Pharmafasching" - bananas....

Nice evening at the "Pharmafasching" - bananas....

Nice evening at the "Pharmafasching" - bananas....

Escape room

The team of Angela, Jana, Manuela, Linus, Sandra and Susanne set a new time record of 38:33 minutes in the Escape Room! Super teamwork!!!

But also the other team around Bea, Frank, Kathrin, Linda, Lisa, Sonja could successfully free themselves from the clutches of the crazy Doctor Eisenbarth!

Recent publications

Krumbein M, Oberman F, Cinnamon Y, Golomb M, May D, Vainer G, Belzer V, Meir K, Fridman I, Haybaeck J, Poelzl G, Kehat I, Beeri R, Kessler SM, Yisraeli JK. 2022. IGF2BP2 is Induced by Stress in the Heart and Mediates Dilated Cardiomyopathy. Commun Biol 2023, 6:1229

Maji RK, Czepukojc B, Scherer M, Tierling S, Cadenas C, Gianmoena K, Gasparoni N, Nordström K, Gasparoni G, Laggai S, Yang X, Sinha A, Ebert P, Falk-Paulsen M, Kinkley S, Hoppstädter J, Chung H-R, Rosenstiel P, Hengstler JG, Walter J, Schulz MH*, Kessler SM*, Kiemer AK*. 2023. Alterations in the hepatocyte epigenetic landscape in steatosis. Epigenetics Chromatin 2023, 16:30

Kendzia S, Franke S, Kröhler T et al. A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer. 2023. Mol Cancer 22:89. https://doi.org/10.1186/s12943-023-01787-x   

Up