Contact

Prof. Dr. Sonja Keßler

room 2.13
Wolfgang-Langenbeck-Str. 4
06120 Halle/Saale

ORCID: 0000-0002-8591-851

Sekretariat: Frau A. Ernst

phone: +49 345 55 25003
fax: +49 345 55 27021

room 2.14
Wolfgang-Langenbeck-Str. 4
06120 Halle/Saale

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Pharmacology and Toxicology for Natural Sciences

Research Group Experimental Pharmacology for Natural Sciences

Kessler lab: April 2026. f.l.t.r. Nicole Glaubitz, Bettina Rahfeld, Susanne Franke, Sonja Keßler, Franziska Frielingsdorf, Beatrice Starke, William Ziem, Theresa Bauchspieß, Angela Ernst, Larissa Wolter, Johannes Kipp, Manuela Thiemicke, Elia Raab, Kathrin Dietze, Nikolaos Giannareas, Lisa Ahne, Frank Erdmann, Linus Wolf.
Missing: Jana Hirschfeld and Sandra Kendzia

Kessler lab: April 2026. f.l.t.r. Nicole Glaubitz, Bettina Rahfeld, Susanne Franke, Sonja Keßler, Franziska Frielingsdorf, Beatrice Starke, William Ziem, Theresa Bauchspieß, Angela Ernst, Larissa Wolter, Johannes Kipp, Manuela Thiemicke, Elia Raab, Kathrin Dietze, Nikolaos Giannareas, Lisa Ahne, Frank Erdmann, Linus Wolf. Missing: Jana Hirschfeld and Sandra Kendzia

Kessler lab: April 2026. f.l.t.r. Nicole Glaubitz, Bettina Rahfeld, Susanne Franke, Sonja Keßler, Franziska Frielingsdorf, Beatrice Starke, William Ziem, Theresa Bauchspieß, Angela Ernst, Larissa Wolter, Johannes Kipp, Manuela Thiemicke, Elia Raab, Kathrin Dietze, Nikolaos Giannareas, Lisa Ahne, Frank Erdmann, Linus Wolf.
Missing: Jana Hirschfeld and Sandra Kendzia

Welcome to the website of the research group Experimental Pharmacology for Natural Sciences at the Institute of Pharmacy.

Further information on projects, staff, and teaching can be found by using the links of the menu.

News

New mechanism in cardiac remodeling and cardiomyopathy! The first paper from a great collaboration with our Israeli colleagues has been published. 10.1038/s42003-023-05547-x    

Also take a look at the press reports:

"Discovery paves the way for innovative therapeutic strategies in managing cardiac conditions"   

"RNA binding protein IGF2BP2 identified as key player in stress-induced dilated cardiomyopathy"   

"Unveiling heart's hidden hero: RNA binding protein IGF2BP2 identified as key player in stress-induced dilated cardiomyopathy"   

"When a big heart isn't a good thing"   

Interested in epigenetics of steatosis? Read our recent article about epigenetic changes in fatty liver disease! https://rdcu.be/dgfMN   

Our paper on the role of IGF2BP2 in colon cancer chemoresistance has been accepted for publication in Molecular Cancer! Check the full paper here:

https://rdcu.be/ddnIb   

Lab events

Pharmafasching

Pharmafasching 2026 - The Keßler Family

Pharmafasching 2026 - The Keßler Family

Pharmafasching 2026 - The Keßler Family

Pharmafasching 2025 - Pharmanauten

Pharmafasching 2025 - Pharmanauten

Pharmafasching 2025 - Pharmanauten

2024 Nice evening at the "Pharmafasching" - bananas....

2024 Nice evening at the "Pharmafasching" - bananas....

2024 Nice evening at the "Pharmafasching" - bananas....

Research group trips

Research group trip to the airport 2025

Research group trip to the airport 2025

Research group trip to the airport 2025

Research group trip to "Bundeswehrapotheke in Blankenburg" 2024

Research group trip to "Bundeswehrapotheke in Blankenburg" 2024

Research group trip to "Bundeswehrapotheke in Blankenburg" 2024

Escape room

The team of Angela, Jana, Manuela, Linus, Sandra and Susanne set a new time record of 38:33 minutes in the Escape Room! Super teamwork!!!

But also the other team around Bea, Frank, Kathrin, Linda, Lisa, Sonja could successfully free themselves from the clutches of the crazy Doctor Eisenbarth!

Recent publications

Herbst M, Kipp J, Kessler SM, Wischke C. Physicochemical and Biological  Characterization of the TLR7 Agonist SZU-106. Pharm Res. 2026 Feb 26.  doi: 10.1007/s11095-026-04031-5. Epub ahead of print. PMID: 41741911.

Blümke J, Schameitat M, Verma A, Limbecker C, Arlt E, Kessler SM,  Kielstein H, Krug S, Bazwinsky-Wutschke I, Haemmerle M. Innate Immunity  and Platelets: Unveiling Their Role in Chronic Pancreatitis and  Pancreatic Cancer. Cancers (Basel). 2025 May 17;17(10):1689. doi:  10.3390/cancers17101689. PMID: 40427186; PMCID: PMC12110028.

Chanda S, Lepikhov K, Dahlem C, Schymik HS, Hoppstädter J, Geber AK,  Wagner K, Kessler SM, Empting M, Kiemer AK. Gene Editing and Small  Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its  Potential as an Anti-Cancer Drug Target. Front Biosci (Landmark Ed).  2024 Jan 23;29(1):41. doi: 10.31083/j.fbl2901041. PMID: 38287808.

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